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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307917
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp1
Name: matrix metallopeptidase 1
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp1decreases expressionISOMMP1 (Homo sapiens)6480464CTDGlucose results in decreased expression of MMP1 mRNAPMID:31655124
Mmp1multiple interactionsISOMmp1b (Mus musculus)6480464CTDGlucose inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]PMID:30098273
Mmp1multiple interactionsISOMMP1 (Homo sapiens)6480464CTDCD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]PMID:18180316
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