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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10468
Species: Mus musculus
RGD Object: Gene
Symbol: Ace
Name: angiotensin I converting enzyme
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aceincreases expressionEXP 6480464CTDGlucose results in increased expression of ACE proteinPMID:29266779
Acemultiple interactionsEXP 6480464CTDCEBPB protein inhibits the reaction [Glucose results in increased expression of ACE protein]PMID:29266779
Acedecreases expressionISOACE (Homo sapiens)6480464CTDGlucose results in decreased expression of ACE mRNAPMID:31655124
Aceincreases expressionISOAce (Rattus norvegicus)6480464CTDGlucose results in increased expression of ACE mRNAPMID:29211853
Aceincreases expressionISOACE (Homo sapiens)6480464CTDGlucose results in increased expression of ACE proteinPMID:16452552
Acemultiple interactionsISOAce (Rattus norvegicus)6480464CTDNFE2L2 protein affects the reaction [Glucose results in increased expression of ACE mRNA]; oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of ACE mRNA]]; trigonelline inhibits the reaction [Glucose results in increased expression of ACE mRNA]PMID:29211853
Acemultiple interactionsISOACE (Homo sapiens)6480464CTDEnalaprilat inhibits the reaction [Glucose results in increased expression of ACE protein]PMID:16452552
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