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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10326
Species: Mus musculus
RGD Object: Gene
Symbol: Cebpb
Name: CCAAT/enhancer binding protein beta
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpbdecreases expressionEXP 6480464CTDGlucose results in decreased expression of CEBPB proteinPMID:29266779
Cebpbmultiple interactionsEXP 6480464CTDCEBPB protein inhibits the reaction [Glucose results in decreased expression of ACE2 protein]; CEBPB protein inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of MMP2 protein]; CEBPB protein inhibits the reaction [Glucose results in decreased expression of MAS1 protein]; CEBPB protein inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of ACE protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR1 protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR2 protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of BAX protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of COL3A1 protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of TGFB1 protein]; Glucose inhibits the reaction [CEBPB protein binds to ACE2 promoter]PMID:28482072 PMID:29266779
Cebpbmultiple interactionsISOCEBPB (Homo sapiens)6480464CTDCEBPB protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPB protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; Glucose promotes the reaction [CEBPB protein binds to EDN1 promoter]; Glucose results in increased localization of and results in increased activity of CEBPB protein; pyrazolanthrone inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]; SB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]; U 0126 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]PMID:24376792
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