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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734191
Species: Homo sapiens
RGD Object: Gene
Symbol: GPT
Name: glutamic--pyruvic transaminase
Acc ID: CHEBI:17230
Term: homocysteine
Definition: A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.
Chemical ID: MESH:D006710
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPTincreases activityISOGpt (Rattus norvegicus)6480464CTDHomocysteine results in increased activity of GPT proteinPMID:33788065
GPTmultiple interactionsISOGpt (Rattus norvegicus)6480464CTDFolic Acid inhibits the reaction [Homocysteine results in increased activity of GPT protein]PMID:33788065
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