GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | increases activity | ISO | RELA (Homo sapiens) | 6480464 | CTD | Homocysteine results in increased activity of RELA protein | PMID:25888188 | Rela | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | Homocysteine results in increased expression of RELA protein | PMID:18540024 | Rela | increases localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | Homocysteine results in increased localization of RELA protein | PMID:17586618 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Homocysteine results in increased activity of RELA protein]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein affects the localization of RELA protein modified form]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of RELA protein]; fulvic acid inhibits the reaction [Homocysteine promotes the reaction [RELA protein binds to PTGS2 promoter]]; Homocysteine promotes the reaction [RELA protein binds to PTGS2 promoter]; pyrazolanthrone inhibits the reaction [Homocysteine results in increased activity of RELA protein] | PMID:24224954 PMID:25888188 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | Homocysteine inhibits the reaction [Simvastatin results in decreased expression of RELA protein] | PMID:18540024 | | ||||||||||||||||||||||
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