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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620690
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Birc2
Name: baculoviral IAP repeat-containing 2
Acc ID: CHEBI:17230
Term: homocysteine
Definition: A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.
Chemical ID: MESH:D006710
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc2decreases expressionISOBIRC2 (Homo sapiens)6480464CTDHomocysteine results in decreased expression of BIRC2 mRNA; Homocysteine results in decreased expression of BIRC2 proteinPMID:19343037
Birc2multiple interactionsISOBIRC2 (Homo sapiens)6480464CTDSimvastatin inhibits the reaction [Homocysteine results in decreased expression of BIRC2 mRNA]; Simvastatin inhibits the reaction [Homocysteine results in decreased expression of BIRC2 protein]PMID:19343037
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