GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nphs2 | decreases expression | ISO | Nphs2 (Mus musculus) | 6480464 | CTD | Homocysteine results in decreased expression of NPHS2 mRNA; Homocysteine results in decreased expression of NPHS2 protein | PMID:20036696 PMID:23024785 | Nphs2 | multiple interactions | ISO | Nphs2 (Mus musculus) | 6480464 | CTD | [Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of NPHS2 mRNA; acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]; acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein]; Amitriptyline inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein]; CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in decreased expression of NPHS2 mRNA]; diphenyleneiodonium inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]; diphenyleneiodonium inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein]; Filipin inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]; Filipin inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein]; methyl-beta-cyclodextrin inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]; methyl-beta-cyclodextrin inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein] | PMID:20036696 PMID:20116427 PMID:23024785 | | ||||||||||||||||||||||
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