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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:17226
Term: rosmarinic acid
Definition: The 1-carboxy-2-(2,4-dihydroxyphenyl)ethyl ester of trans-caffeic acid.
Chemical ID: MESH:C041376
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaaffects expressionEXP 6480464CTDrosmarinic acid affects the expression of RELA mRNA, rosmarinic acid affects the expression of RELA protein

PMID:28744220
Relaaffects localizationEXP 6480464CTDrosmarinic acid affects the localization of RELA protein

PMID:25455894
Reladecreases phosphorylationEXP 6480464CTDrosmarinic acid results in decreased phosphorylation of RELA protein

PMID:28789951
Relamultiple interactionsEXP 6480464CTD2-chloro-5-nitrobenzanilide inhibits the reaction [rosmarinic acid affects the expression of RELA mRNA], 2-chloro-5-nitrobenzanilide inhibits the reaction [rosmarinic acid affects the expression of RELA protein], T 0070907 inhibits the reaction [rosmarinic acid affects the expression of RELA mRNA], T 0070907 inhibits the reaction [rosmarinic acid affects the expression of RELA protein]

PMID:28744220
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