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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:17226
Term: rosmarinic acid
Definition: The 1-carboxy-2-(2,4-dihydroxyphenyl)ethyl ester of trans-caffeic acid.
Chemical ID: MESH:C041376
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTDrosmarinic acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]

PMID:28815802
Casp3multiple interactionsISORGD:102896480464CTDrosmarinic acid inhibits the reaction [Cadmium results in increased activity of CASP3 protein]

PMID:23548128
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.