GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nqo1 | decreases expression | ISO | Nqo1 (Rattus norvegicus) | 6480464 | CTD | sanguinarine results in decreased expression of NQO1 mRNA; sanguinarine results in decreased expression of NQO1 protein | PMID:24300172 | Nqo1 | decreases expression | ISO | NQO1 (Homo sapiens) | 6480464 | CTD | sanguinarine results in decreased expression of NQO1 mRNA; sanguinarine results in decreased expression of NQO1 protein | PMID:22021338 | Nqo1 | increases reduction | ISO | Nqo1 (Rattus norvegicus) | 6480464 | CTD | NQO1 protein results in increased reduction of sanguinarine | PMID:24300172 | Nqo1 | multiple interactions | ISO | Nqo1 (Rattus norvegicus) | 6480464 | CTD | NQO1 protein inhibits the reaction [sanguinarine results in decreased expression of BCL2 mRNA]; NQO1 protein inhibits the reaction [sanguinarine results in decreased expression of BCL2 protein]; NQO1 protein inhibits the reaction [sanguinarine results in increased expression of BAX mRNA]; NQO1 protein inhibits the reaction [sanguinarine results in increased expression of BAX protein] | PMID:24300172 | |
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