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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303073
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xbp1
Name: X-box binding protein 1
Acc ID: CHEBI:171741
Term: cerulenin
Definition: An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.
Chemical ID: MESH:D002569
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xbp1multiple interactionsISOXBP1 (Homo sapiens)6480464CTDCerulenin affects the reaction [ERN1 protein affects the splicing of XBP1 mRNA]PMID:17283163
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