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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733181
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh3a1
Name: aldehyde dehydrogenase family 3, subfamily A1
Acc ID: CHEBI:17169
Term: benzaldehyde
Definition: An arenecarbaldehyde that consists of benzene bearing a single formyl substituent; the simplest aromatic aldehyde and parent of the class of benzaldehydes.
Chemical ID: MESH:C032175
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh3a1increases metabolic processingEXP 6480464CTDALDH3A1 protein results in increased metabolism of benzaldehydePMID:21256123
Aldh3a1increases oxidationISOALDH3A1 (Homo sapiens)6480464CTDALDH3A1 protein results in increased oxidation of benzaldehydePMID:21349255 PMID:23220590 PMID:25512087
Aldh3a1multiple interactionsISOALDH3A1 (Homo sapiens)6480464CTD[ALDH3A1 protein co-treated with NAD] results in increased oxidation of benzaldehyde; [ALDH3A1 protein co-treated with NADP] results in increased oxidation of benzaldehyde; Cimetidine inhibits the reaction [ALDH3A1 protein results in increased oxidation of benzaldehyde]PMID:10856427 PMID:23220590
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