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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:17158
Term: methylglyoxal
Definition: A 2-oxo aldehyde derived from propanal.
Chemical ID: MESH:D011765
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDPyruvaldehyde results in increased expression of BAX proteinPMID:34455488
Baxmultiple interactionsEXP 6480464CTDPhosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein]PMID:34455488
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDPyruvaldehyde results in increased expression of BAX proteinPMID:26577515 PMID:31254498
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTDnaringenin inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein]PMID:26577515 PMID:31254498
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