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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731903
Species: Homo sapiens
RGD Object: Gene
Symbol: DLG1
Name: discs large MAGUK scaffold protein 1
Acc ID: CHEBI:17154
Term: nicotinamide
Definition: A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Chemical ID: MESH:D009536
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DLG1multiple interactionsISODlg1 (Mus musculus)6480464CTD[Niacinamide results in decreased activity of SIRT1 protein] which results in decreased expression of DLG1 mRNA; Niacinamide inhibits the reaction [geranylgeranylacetone results in increased expression of DLG1 mRNA]PMID:21232033
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