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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307153
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chac1
Name: ChaC glutathione-specific gamma-glutamylcyclotransferase 1
Acc ID: CHEBI:17151
Term: xylitol
Definition: A pentitol (five-carbon sugar alcohol) having meso-configuration, being derived from xylose by reduction of the carbonyl group.
Chemical ID: MESH:D014993
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chac1increases expressionISOCHAC1 (Homo sapiens)6480464CTDXylitol results in increased expression of CHAC1 mRNA; Xylitol results in increased expression of CHAC1 proteinPMID:32275922
Chac1multiple interactionsISOCHAC1 (Homo sapiens)6480464CTDursodoxicoltaurine inhibits the reaction [Xylitol results in increased expression of CHAC1 protein]PMID:32275922
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