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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346384
Species: Homo sapiens
RGD Object: Gene
Symbol: MPO
Name: myeloperoxidase
Acc ID: CHEBI:17141
Term: cysteamine
Definition: An amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2.
Chemical ID: MESH:D003543
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MPOincreases expressionISOMpo (Rattus norvegicus)6480464CTDCysteamine results in increased expression of MPO proteinPMID:20165931 PMID:24337826
MPOmultiple interactionsISOMpo (Rattus norvegicus)6480464CTDgeraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; thamira parpam inhibits the reaction [Cysteamine results in increased expression of MPO protein]PMID:20165931 PMID:24337826
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