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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1597139
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Idh2
Name: isocitrate dehydrogenase (NADP(+)) 2
Acc ID: CHEBI:17050
Term: 3-phosphoglyceric acid
Definition: A monophosphoglyceric acid having the phospho group at the 3-position. It is an intermediate in metabolic pathways like glycolysis and calvin cycle.
Chemical ID: MESH:C005156
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Idh2increases abundanceISOIdh2 (Mus musculus)6480464CTDIDH2 protein mutant form results in increased abundance of 3-phosphoglyceratePMID:27469509
Idh2multiple interactionsISOIdh2 (Mus musculus)6480464CTDTriazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 3-phosphoglycerate]PMID:27469509
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