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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Defb4
Name: defensin beta 4
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13487946480464CTDProgesterone results in increased expression of DEFB4A mRNA

PMID:19819163
multiple interactionsISORGD:13487946480464CTDLipopolysaccharides inhibits the reaction [Progesterone results in increased expression of DEFB4A mRNA]

PMID:19819163
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