Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61967
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcm6
Name: minichromosome maintenance complex component 6
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcm6decreases expressionEXP 6480464CTDProgesterone results in decreased expression of MCM6 mRNAPMID:20726854
Mcm6affects localizationISOMcm6 (Mus musculus)6480464CTDProgesterone affects the localization of MCM6 proteinPMID:16966611
Mcm6decreases expressionISOMcm6 (Mus musculus)6480464CTDProgesterone results in decreased expression of MCM6 mRNAPMID:16966611
Mcm6multiple interactionsISOMcm6 (Mus musculus)6480464CTDEstradiol inhibits the reaction [Progesterone affects the localization of MCM6 protein]PMID:16966611
Go Back to source page   Continue to Ontology report