GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lhb | increases secretion | EXP | | 6480464 | CTD | LHB protein results in increased secretion of Progesterone | PMID:22247282 | Lhb | multiple interactions | EXP | | 6480464 | CTD | 7-Ala-angiotensin (1-7) inhibits the reaction [LHB protein results in increased secretion of Progesterone]; [Estradiol co-treated with Progesterone] results in decreased secretion of LHB protein; [Estradiol co-treated with Progesterone] results in increased expression of LHB protein; Atrazine inhibits the reaction [[estradiol 3-benzoate co-treated with Progesterone] results in increased secretion of LHB protein]; nociceptin (1-13) amide inhibits the reaction [PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein]]; PNOC protein inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased expression of LHB protein] | PMID:15056801 PMID:17640482 PMID:19215433 PMID:22247282 | Lhb | decreases abundance | ISO | LHB (Homo sapiens) | 6480464 | CTD | LHB protein results in decreased abundance of Progesterone | PMID:23433069 | Lhb | increases abundance | ISO | Lhb (Mus musculus) | 6480464 | CTD | LHB protein results in increased abundance of Progesterone | PMID:21220312 | Lhb | increases abundance | ISO | LHB (Homo sapiens) | 6480464 | CTD | LHB protein results in increased abundance of Progesterone | PMID:19926922 | Lhb | increases secretion | ISO | Lhb (Mus musculus) | 6480464 | CTD | LHB protein results in increased secretion of Progesterone | PMID:34627990 | Lhb | increases secretion | ISO | LHB (Homo sapiens) | 6480464 | CTD | LHB protein results in increased secretion of Progesterone | PMID:15525572 PMID:15967414 PMID:33638691 | Lhb | multiple interactions | ISO | Lhb (Mus musculus) | 6480464 | CTD | [estradiol 3-benzoate co-treated with Progesterone] results in increased abundance of LHB protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased secretion of Progesterone]; Reactive Oxygen Species promotes the reaction [LHB protein results in increased abundance of Progesterone] | PMID:21220312 PMID:22577852 PMID:34627990 | Lhb | multiple interactions | ISO | LHB (Homo sapiens) | 6480464 | CTD | [LHB protein affects the secretion of Cyclic AMP] which results in increased secretion of Progesterone; ADCYAP1R1 protein promotes the reaction [LHB protein results in increased abundance of Progesterone]; DDT inhibits the reaction [LHB protein results in increased secretion of Progesterone]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased secretion of Progesterone] | PMID:15967414 PMID:19926922 PMID:23071612 PMID:33638691 | | ||||||||||||||||||||||
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