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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353256
Species: Homo sapiens
RGD Object: Gene
Symbol: F2
Name: coagulation factor II, thrombin
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F2multiple interactionsEXP 6480464CTD[Hirudins binds to and results in decreased activity of F2 protein] promotes the reaction [CGB3 protein results in increased chemical synthesis of Progesterone]PMID:22207716
F2multiple interactionsISOF2 (Mus musculus)6480464CTD[Hirudins binds to and results in decreased activity of F2 protein] which results in increased chemical synthesis of ProgesteronePMID:22207716
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