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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2149
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Areg
Name: amphiregulin
Acc ID: CHEBI:16990
Term: bilirubin IXalpha
Definition: A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.
Chemical ID: MESH:D001663
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aregincreases expressionISOAREG (Homo sapiens)6480464CTDBilirubin results in increased expression of AREG mRNAPMID:20196124
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