GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcc1 | affects binding | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | Leukotriene C4 analog binds to ABCC1 protein | PMID:15628876 | Abcc1 | affects transport | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | ABCC1 protein affects the transport of Leukotriene C4 | PMID:11278867 | Abcc1 | decreases transport | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | ABCC1 protein mutant form results in decreased transport of Leukotriene C4 | PMID:18336795 | Abcc1 | increases uptake | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | ABCC1 protein results in increased uptake of Leukotriene C4 | PMID:11306701 | Abcc1 | multiple interactions | ISO | ABCC1 (Homo sapiens) | 6480464 | CTD | [Nimustine results in increased expression of ABCC1 protein] which results in increased transport of Leukotriene C4; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Leukotriene C4]; Apigenin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]; Bilirubin inhibits the reaction [ABCC1 protein affects the transport of Leukotriene C4]; estradiol-17 beta-glucuronide inhibits the reaction [ABCC1 protein affects the transport of Leukotriene C4]; Genistein affects the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]; Glutathione Disulfide promotes the reaction [Leukotriene C4 analog binds to ABCC1 protein]; Glutathione promotes the reaction [Apigenin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]]; Glutathione promotes the reaction [Genistein affects the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]]; Glutathione promotes the reaction [naringenin affects the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]]; kaempferol inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]; myricetin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]; naringenin affects the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]; Quercetin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4] | PMID:11278867 PMID:11306701 PMID:15245331 PMID:15355964 PMID:15459206 PMID:15628876 PMID:9393752 | |
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