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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347936
Species: Homo sapiens
RGD Object: Gene
Symbol: VWF
Name: von Willebrand factor
Acc ID: CHEBI:16933
Term: ergosterol
Definition: A phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group.
Chemical ID: MESH:D004875
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VWFmultiple interactionsISOVwf (Rattus norvegicus)6480464CTD[Cholesterol co-treated with Ergosterol] results in increased expression of and results in increased secretion of VWF protein; resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of and results in increased secretion of VWF protein]PMID:25833014
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