GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PTGS2 | multiple interactions | EXP | | 6480464 | CTD | [4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of PTGS2 mRNA; nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of PTGS2 mRNA] | PMID:20043093 | PTGS2 | decreases response to substance | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | PTGS2 gene mutant form results in decreased susceptibility to 4-Nitroquinoline-1-oxide | PMID:20857495 | PTGS2 | increases expression | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | 4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein | PMID:28397014 | PTGS2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | 4-Nitroquinoline-1-oxide results in increased expression of PTGS2 mRNA; 4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein | PMID:22561872 | PTGS2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein] | PMID:28397014 | PTGS2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | Zinc deficiency inhibits the reaction [PTGS2 gene mutant form results in decreased susceptibility to 4-Nitroquinoline-1-oxide] | PMID:20857495 | | ||||||||||||||||||||||
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