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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3185
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2
Acc ID: CHEBI:16905
Term: keto-D-fructose 1,6-bisphosphate
Definition: A ketohexose bisphosphate that is D-fructose substituted by phosphate groups at positions 1 and 6.
Chemical ID: MESH:C029063
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2decreases degradationISORGD:109966480464CTDfructose-1 6-diphosphate results in decreased degradation of NOS2 mRNA

PMID:22227475
Nos2multiple interactionsISORGD:109966480464CTDfructose-1 6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] fructose-1 6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]

PMID:22227475
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