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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10436
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:16866
Term: alizarin
Definition: A dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2.
Chemical ID: MESH:C010078
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1decreases activityISOCYP1A1 (Homo sapiens)6480464CTDalizarin results in decreased activity of CYP1A1 proteinPMID:12379470 PMID:37515497
Cyp1a1multiple interactionsISOCYP1A1 (Homo sapiens)6480464CTDalizarin affects the reaction [Benzo(a)pyrene affects the activity of CYP1A1 protein]PMID:37515497
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