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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620505
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Crh
Name: corticotropin releasing hormone
Acc ID: CHEBI:16865
Term: gamma-aminobutyric acid
Definition: A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Chemical ID: MESH:D005680
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Crhmultiple interactionsEXP 6480464CTDgamma-Aminobutyric Acid inhibits the reaction [acephate results in increased expression of CRH mRNA]; gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased secretion of CRH protein]; gamma-Aminobutyric Acid inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; gamma-Aminobutyric Acid inhibits the reaction [methamidophos results in increased secretion of CRH protein]PMID:12039681
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