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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736610
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1b1
Name: aldo-keto reductase family 1 member B
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b1affects bindingISOAKR1B1 (Homo sapiens)6480464CTDAKR1B1 protein binds to GlutathionePMID:11306073
Akr1b1increases glutathionylationISOAKR1B1 (Homo sapiens)6480464CTDGlutathione results in increased glutathionylation of AKR1B1 protein modified formPMID:19061876
Akr1b1increases reductionISOAKR1B1 (Homo sapiens)6480464CTDGlutathione results in increased reduction of AKR1B1 protein modified formPMID:19061876
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