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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735748
Species: Mus musculus
RGD Object: Gene
Symbol: Snca
Name: synuclein, alpha
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sncadecreases abundanceISOSNCA (Homo sapiens)6480464CTDSNCA protein results in decreased abundance of GlutathionePMID:27026137 PMID:27424009
Sncamultiple interactionsISOSnca (Rattus norvegicus)6480464CTDGlutathione inhibits the reaction [manganese chloride promotes the reaction [SNCA protein binds to SNCA protein binds to SNCA protein]]PMID:23353026
Sncamultiple interactionsISOSNCA (Homo sapiens)6480464CTDDopamine inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]; ferrous sulfate inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]PMID:27026137 PMID:27424009
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