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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2139
Species: Rattus norvegicus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appdecreases abundanceEXP 6480464CTDAPP protein modified form results in decreased abundance of GlutathionePMID:25654502
Appmultiple interactionsEXP 6480464CTDresveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Glutathione]PMID:25654502
Appdecreases abundanceISOApp (Mus musculus)6480464CTDAPP protein modified form results in decreased abundance of GlutathionePMID:29545167
Appmultiple interactionsISOApp (Mus musculus)6480464CTDvitexin inhibits the reaction [APP protein modified form results in decreased abundance of Glutathione]PMID:29545167
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