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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303284
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpa1multiple interactionsISOTRPA1 (Homo sapiens)6480464CTDGlutathione inhibits the reaction [agathic acid results in increased activity of TRPA1 protein]; Glutathione inhibits the reaction [Particulate Matter results in increased activity of TRPA1 protein]; Glutathione inhibits the reaction [phenalen-1-one results in increased activity of TRPA1 protein]PMID:23541125 PMID:30945539
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