GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620410
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ltb4r
Name: leukotriene B4 receptor
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases response to substanceEXP 6480464CTDLTB4R protein results in increased susceptibility to Formaldehyde

PMID:19835937
multiple interactionsEXP 6480464CTDMK-886 inhibits the reaction [LTB4R protein results in increased susceptibility to Formaldehyde]

PMID:19835937
increases expressionISORGD:13480206480464CTDFormaldehyde results in increased expression of LTB4R mRNA

PMID:23649840
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.