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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731073
Species: Mus musculus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:16827
Term: corticosterone
Definition: A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
Chemical ID: MESH:D003345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfaaffects expressionEXP 6480464CTDCorticosterone affects the expression of VEGFA proteinPMID:21647420
Vegfaincreases expressionEXP 6480464CTDCorticosterone results in increased expression of VEGFA proteinPMID:21647420
Vegfamultiple interactionsISOVegfa (Rattus norvegicus)6480464CTDCorticosterone inhibits the reaction [TGFB1 protein results in increased secretion of VEGFA protein]PMID:16598785
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