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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62346
Species: Mus musculus
RGD Object: Gene
Symbol: Pdyn
Name: prodynorphin
Acc ID: CHEBI:16827
Term: corticosterone
Definition: A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
Chemical ID: MESH:D003345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdynmultiple interactionsEXP 6480464CTDPDYN protein promotes the reaction [Cocaine results in increased abundance of Corticosterone]PMID:17532787
Pdynmultiple interactionsISOPdyn (Rattus norvegicus)6480464CTDCorticosterone inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of PDYN mRNA]PMID:18687386
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