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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2157
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arrb2
Name: arrestin, beta 2
Acc ID: CHEBI:16827
Term: corticosterone
Definition: A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
Chemical ID: MESH:D003345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arrb2decreases expressionISOArrb2 (Mus musculus)6480464CTDCorticosterone results in decreased expression of ARRB2 mRNAPMID:19477151
Arrb2multiple interactionsISOArrb2 (Mus musculus)6480464CTDFluoxetine inhibits the reaction [Corticosterone results in decreased expression of ARRB2 mRNA]PMID:19477151
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