GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFE2L2 | increases expression | EXP | | 6480464 | CTD | Melatonin results in increased expression of NFE2L2 mRNA | PMID:33962019 | NFE2L2 | multiple interactions | EXP | | 6480464 | CTD | Melatonin inhibits the reaction [cyfluthrin results in increased expression of NFE2L2 mRNA] | PMID:31330490 | NFE2L2 | increases expression | ISO | Nfe2l2 (Rattus norvegicus) | 6480464 | CTD | Melatonin results in increased expression of NFE2L2 protein | PMID:20433640 | NFE2L2 | increases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Melatonin results in increased expression of NFE2L2 protein | PMID:25288107 | NFE2L2 | multiple interactions | ISO | Nfe2l2 (Rattus norvegicus) | 6480464 | CTD | Melatonin inhibits the reaction [[Dietary Fats co-treated with Ethanol] results in decreased expression of NFE2L2 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 protein]; Melatonin promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFE2L2 protein] | PMID:20433640 PMID:30372842 PMID:35598369 | NFE2L2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | 4-phenyl-2-propionamidotetraline inhibits the reaction [Melatonin inhibits the reaction [KL mutant form affects the localization of and results in decreased activity of NFE2L2 protein]]; [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of NFE2L2 protein; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein]]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein]; Melatonin inhibits the reaction [KL mutant form affects the localization of and results in decreased activity of NFE2L2 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of NFE2L2 protein]; Melatonin inhibits the reaction [Ozone promotes the reaction [Ovalbumin results in decreased expression of NFE2L2 mRNA]]; SL 327 inhibits the reaction [Melatonin inhibits the reaction [KL mutant form affects the localization of and results in decreased activity of NFE2L2 protein]] | PMID:25288107 PMID:25550330 PMID:27871981 PMID:34146326 PMID:37598416 | | ||||||||||||||||||||||
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