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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733618
Species: Homo sapiens
RGD Object: Gene
Symbol: DNM1L
Name: dynamin 1 like
Acc ID: CHEBI:16796
Term: melatonin
Definition: A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans.
Chemical ID: MESH:D008550
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DNM1Lmultiple interactionsEXP 6480464CTDMelatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA]; Melatonin inhibits the reaction [Rotenone results in increased expression of DNM1L protein]PMID:29183837 PMID:33962019
DNM1Lmultiple interactionsISODnm1l (Rattus norvegicus)6480464CTDMelatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of DNM1L protein]; Melatonin inhibits the reaction [Doxorubicin results in increased expression of DNM1L protein]PMID:26882442 PMID:29966675
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