GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ACHE | increases activity | EXP | | 6480464 | CTD | Scopolamine results in increased activity of ACHE protein | PMID:20694781 | ACHE | multiple interactions | EXP | | 6480464 | CTD | kangshuai yizhi inhibits the reaction [Scopolamine results in increased activity of ACHE protein] | PMID:20694781 | ACHE | affects activity | ISO | Ache (Mus musculus) | 6480464 | CTD | Scopolamine affects the activity of ACHE protein | PMID:26434561 | ACHE | affects response to substance | ISO | Ache (Mus musculus) | 6480464 | CTD | ACHE affects the susceptibility to Scopolamine | PMID:18672024 | ACHE | decreases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Scopolamine results in decreased activity of ACHE protein | PMID:11814146 | ACHE | decreases expression | ISO | Ache (Mus musculus) | 6480464 | CTD | Scopolamine results in decreased expression of ACHE protein | PMID:22426032 | ACHE | increases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Scopolamine results in increased activity of ACHE protein | PMID:20871768 PMID:28837785 | ACHE | increases activity | ISO | Ache (Mus musculus) | 6480464 | CTD | Scopolamine results in increased activity of ACHE protein | PMID:15301936 PMID:20673844 PMID:26408985 PMID:27717698 PMID:29133030 PMID:34371027 | ACHE | increases expression | ISO | Ache (Mus musculus) | 6480464 | CTD | Scopolamine results in increased expression of ACHE mRNA; Scopolamine results in increased expression of ACHE protein | PMID:26434561 PMID:31077737 PMID:32001261 | ACHE | increases response to substance | ISO | Ache (Mus musculus) | 6480464 | CTD | ACHE protein results in increased susceptibility to Scopolamine | PMID:18533140 | ACHE | multiple interactions | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Ascorbic Acid inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]; Canagliflozin inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Galantamine inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; stevioside inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Vitamin E inhibits the reaction [Scopolamine results in decreased activity of ACHE protein] | PMID:11814146 PMID:20871768 PMID:28837785 | ACHE | multiple interactions | ISO | Ache (Mus musculus) | 6480464 | CTD | 7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in increased expression of ACHE protein]; acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein]; ajoene inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; chong-myung-tang inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; dihydroactinidiolide inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; mangiferin inhibits the reaction [Scopolamine results in decreased expression of ACHE protein]; Piracetam inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Plant Extracts affects the reaction [Scopolamine affects the activity of ACHE protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of ACHE mRNA]; protopanaxadiol inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of ACHE protein] | PMID:15301936 PMID:20673844 PMID:22426032 PMID:26408985 PMID:26434561 PMID:27717698 PMID:29133030 PMID:31077737 PMID:32001261 PMID:34371027 | | ||||||||||||||||||||||
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