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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343954
Species: Homo sapiens
RGD Object: Gene
Symbol: PDYN
Name: prodynorphin
Acc ID: CHEBI:16794
Term: scopolamine
Definition: A tropane alkaloid that is the (S)-tropic acid ester of 6beta,7beta-epoxy-1alphaH,5alphaH-tropan-3alpha-ol.
Chemical ID: MESH:D012601
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDYNdecreases response to substanceISOPdyn (Mus musculus)6480464CTDPDYN protein modified form results in decreased susceptibility to ScopolaminePMID:7768285
PDYNincreases expressionISOPdyn (Rattus norvegicus)6480464CTDScopolamine results in increased expression of PDYN mRNAPMID:17540011
PDYNmultiple interactionsISOPdyn (Mus musculus)6480464CTDMR 2266 inhibits the reaction [PDYN protein modified form results in decreased susceptibility to Scopolamine]PMID:7768285
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