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RGD ID: 2411
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Crp
Name: C-reactive protein
Acc ID: CHEBI:167707
Term: acalabrutinib
Definition: A member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazine substituted by 4-(pyridin-2-ylcarbamoyl)phenyl, (2S)-1-(but-2-ynoyl)pyrrolidin-2-yl, and amino groups at positions 1, 3 and 8, respectively. It is an irreversible second-generation Bruton's tyrosine kinase (BTK) inhibitor that is approved by the FDA for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy.
Chemical ID: MESH:C000604908
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Crpaffects expressionISOCRP (Homo sapiens)6480464CTDacalabrutinib affects the expression of CRP proteinPMID:32503877
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