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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621681
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2ry12
Name: purinergic receptor P2Y12
Acc ID: CHEBI:16761
Term: ADP
Definition: A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase.
Chemical ID: MESH:D000244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2ry12affects response to substanceEXP 6480464CTDP2RY12 protein affects the susceptibility to Adenosine Diphosphate

PMID:11196645
P2ry12affects response to substanceISORGD:13540006480464CTDP2RY12 gene polymorphism affects the susceptibility to Adenosine Diphosphate P2RY12 protein affects the susceptibility to Adenosine Diphosphate

PMID:11196645 PMID:23849096
P2ry12increases response to substanceISORGD:7335686480464CTDP2RY12 protein results in increased susceptibility to Adenosine Diphosphate

PMID:11413167
P2ry12multiple interactionsISORGD:13540006480464CTDP2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]

PMID:18404433
P2ry12multiple interactionsISORGD:7335686480464CTDEpinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate]

PMID:11413167
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