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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3656
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Selp
Name: selectin P
Acc ID: CHEBI:16761
Term: ADP
Definition: A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase.
Chemical ID: MESH:D000244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Selpincreases expressionISORGD:7371626480464CTDAdenosine Diphosphate results in increased expression of SELP protein

PMID:23249183
Selpmultiple interactionsISORGD:7371626480464CTDcangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein] CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein] Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein] N6-methyl-2'-deoxyadenosine 3' 5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein] N6-methyl-2'-deoxyadenosine 3' 5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]] P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein] Quercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein]

PMID:18394438 PMID:18404433 PMID:23249183 PMID:9740346
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