GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr0b2 | increases expression | EXP | | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA | PMID:15980055 PMID:16357303 PMID:27743861 PMID:29222744 | Nr0b2 | multiple interactions | EXP | | 6480464 | CTD | [Chenodeoxycholic Acid binds to NR1H4 protein] which results in increased expression of NR0B2 mRNA | PMID:19562681 | Nr0b2 | increases expression | ISO | NR0B2 (Homo sapiens) | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA | PMID:16037943 PMID:16269825 PMID:16946559 PMID:19072826 PMID:19562681 PMID:22178739 PMID:22291955 PMID:22540009 PMID:25055961 PMID:27174168 | Nr0b2 | increases expression | ISO | Nr0b2 (Mus musculus) | 6480464 | CTD | Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA | PMID:16946559 PMID:24189133 PMID:25582706 | Nr0b2 | multiple interactions | ISO | NR0B2 (Homo sapiens) | 6480464 | CTD | 7-hydroxytheonellasterol inhibits the reaction [Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA]; [Chenodeoxycholic Acid binds to and results in increased activity of NR1H4 protein] which results in increased expression of NR0B2 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of NR0B2 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of NR0B2 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Triclosan] results in increased expression of NR0B2 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of NR0B2 mRNA; epigallocatechin gallate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA]; NR1H4 affects the reaction [Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA] | PMID:17963371 PMID:19072826 PMID:22178739 PMID:22291955 PMID:33819548 | Nr0b2 | multiple interactions | ISO | Nr0b2 (Mus musculus) | 6480464 | CTD | Chenodeoxycholic Acid inhibits the reaction [tris(chloroethyl)phosphate results in decreased expression of NR0B2 protein]; Chenodeoxycholic Acid promotes the reaction [Carbon Tetrachloride results in decreased expression of NR0B2 mRNA]; NR1H4 protein promotes the reaction [Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA] | PMID:16946559 PMID:25747392 PMID:35780845 | |
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