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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61807
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxm1
Name: forkhead box M1
Acc ID: CHEBI:16755
Term: chenodeoxycholic acid
Definition: A dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively.
Chemical ID: MESH:D002635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxm1increases expressionISOFoxm1 (Mus musculus)6480464CTDChenodeoxycholic Acid results in increased expression of FOXM1 mRNAPMID:22135065
Foxm1multiple interactionsISOFoxm1 (Mus musculus)6480464CTDChenodeoxycholic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of FOXM1 mRNA]; NR1H4 affects the reaction [Chenodeoxycholic Acid results in increased expression of FOXM1 mRNA]PMID:22135065 PMID:25747392
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