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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735652
Species: Homo sapiens
RGD Object: Gene
Symbol: AR
Name: androgen receptor
Acc ID: CHEBI:16738
Term: 2,4-dichlorophenol
Definition: A dichlorophenol that is phenol carrying chloro substituents at positions 2 and 4.
Chemical ID: MESH:C004762
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ARmultiple interactionsEXP 6480464CTD2,4-dichlorophenol inhibits the reaction [Androgens binds to AR protein]; 2,4-dichlorophenol promotes the reaction [Dihydrotestosterone results in increased localization of and results in increased activity of AR protein]PMID:16107550
ARaffects activityISOAr (Mus musculus)6480464CTD2,4-dichlorophenol affects the activity of AR proteinPMID:18294747
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