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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3916
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ttr
Name: transthyretin
Acc ID: CHEBI:167162
Term: L-ascorbic acid 2-phosphate
Definition: An aldonolactone phosphate that is the 2-phosphate ester of L-ascorbic acid. It can stimulate collagen formation.
Chemical ID: MESH:C011669
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ttrmultiple interactionsISOTTR (Homo sapiens)6480464CTD[[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNAPMID:34480604
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