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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312011
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Shmt1
Name: serine hydroxymethyltransferase 1
Acc ID: CHEBI:16709
Term: pyridoxine
Definition: A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.
Chemical ID: MESH:D011736
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Shmt1multiple interactionsISORGD:13237706480464CTDPyridoxine affects the expression of and affects the activity of SHMT1 protein

PMID:17482557
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