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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735816
Species: Mus musculus
RGD Object: Gene
Symbol: Slc22a3
Name: solute carrier family 22 (organic cation transporter), member 3
Acc ID: CHEBI:16684
Term: atropine
Definition: A racemate composed of equimolar concentrations of (S)- and (R)-atropine . It is obtained from deadly nightshade (Atropa belladonna) and other plants of the family Solanaceae.
Chemical ID: MESH:D001285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a3increases uptakeISOSLC22A3 (Homo sapiens)6480464CTDSLC22A3 protein results in increased uptake of AtropinePMID:16263091
Slc22a3multiple interactionsISOSLC22A3 (Homo sapiens)6480464CTDAtropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]PMID:16263091
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