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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733529
Species: Mus musculus
RGD Object: Gene
Symbol: Keap1
Name: kelch-like ECH-associated protein 1
Acc ID: CHEBI:16675
Term: quinolinic acid
Definition: A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Chemical ID: MESH:D017378
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Keap1multiple interactionsISOKeap1 (Rattus norvegicus)6480464CTDQuinolinic Acid promotes the reaction [DPP3 protein binds to KEAP1 protein]; Quinolinic Acid promotes the reaction [SQSTM1 protein binds to KEAP1 protein]; Quinolinic Acid results in increased expression of and affects the localization of KEAP1 proteinPMID:30876764
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